Borane Reagents: A Practical Guide to Procurement, Selection, Storage, and Transportation
Borane reagents are widely used in organic synthesis, pharmaceutical manufacturing, fine chemicals, and materials-related applications because of their high reactivity and useful reduction and hydroboration chemistry. However, sourcing borane reagents is not simply a matter of selecting a product and comparing prices. Different borane complexes and formulations can have different reactivity, concentration, solvent compatibility, storage […]
Thiol-Functionalized Silica Metal Scavengers for Palladium and Heavy Metal Removal
In modern pharmaceutical manufacturing, transition metal catalysts such as palladium, ruthenium, rhodium, and platinum are widely used in critical synthetic reactions. However, residual metals after these reactions can become some of the most challenging impurities to control in pharmaceutical intermediates and active pharmaceutical ingredients (APIs). With the increasing implementation of the ICH Q3D Elemental Impurities […]